Since this game mode is centered on the standard format, the rotation generates a reset of the packets offered
Of course, this means you need a character on board that can initiate the challenge before Maid Marian gets value, but there are 11 4-cost characters that all have decent Strength values, so it isn't hard to get something down the previous turn that can take the Challenge
Luckily while you wait for this to happen, you can draw cards and lose life for exiling cards from your graveyard and/or battlefield, giving Ketramose, the New Dawn some early game relevance before it becomes a game-ender
First it immediately replaces itself drawing a card, gaining 4 puts you out of reach of Lava Spike (Omnath, Locus of Creation + Fetch Land is usually concession from Burn decks)
Eldritch Moon's last new mechanic, Escalate, has a couple of cards that were spoiled in this article from Wizards of the Coast, the first of which is the Instant-speed Borrowed Malevolence
